BDBM50027536 (phosphonoformate)Trisodium phosphonoformate::Antiviral agent : Inhibitor of reverse transcriptase of Human T-cell lymphotropic, virus type III, useful in the treatment of HSV-1 infections::CHEMBL754::EHB-776::FOSCARNET SODIUM::Foscarnet::Foscavir::phosphonoformate trisodium salt::trisodium dioxidophosphinecarboxylate oxide::trisodium dioxidophosphinecarboxylate oxide with 6 molecules of water(foscarnet)::trisodium phosphonoformate

SMILES [O-]C(=O)P([O-])([O-])=O

InChI Key InChIKey=ZJAOAACCNHFJAH-UHFFFAOYSA-K

Data  14 KI  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50027536   

TargetDNA polymerase catalytic subunit(Human herpesvirus 1 (strain 17) (HHV-1) (Human her...)
TBA

Curated by ChEMBL
LigandPNGBDBM50027536((phosphonoformate)Trisodium phosphonoformate | Ant...)
Affinity DataIC50:  7.40E+4nMAssay Description:Inhibition of HSV-1 DNA polymerase in HSV-1 C42 plaque reduction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed